Breakthrough in Pet Dental and Skin Care
Kalzyme is an innovative enzyme-based solution for dental and skin conditions that work together with your pet's natural defences to them live a happier and healthier life.
The Minds Behind Kalzyme
A researcher's and veterinarian's shared vision.
Dr. Alissa Rexo
Mats Clarsund
Dr. Alissa Rexo
DVM, CVA, DACVD Diplomat of the American College of Veterinary Dermatology
Dr. Alissa Rexo is a board-certified veterinary dermatologist known for her expertise in diagnosing and treating skin, ear, and allergy disorders in animals.
As a veterinarian, Alissa often encountered pet health products with questionable efficacy, driving her to develop Kalzyme with Mats.
Mats Clarsund
CTO, ZymIQ ABPh.D in Enzyme engineering & Biotechnology
Mats Clarsund is a Swedish enzyme researcher with extensive experience, having authored/co-authored 36 peer-reviewed publications, including 8 patent applications.
Mats' ambition to find safer and more effective solutions to our pets' dermal and dental challenges drove him to developing a solution with Alissa.
Our pets' mouths host a many microorganisms like bacteria that coexist harmoniously with their immune system. This is the oral microbiome.
A balanced microbiome naturally defends against harmful bacteria by outcompeting them for resources.
An imbalance, caused by harmful bacteria overgrowth, can lead to infections and dental disease.
Dental plaque, a bacterial biofilm, begins forming within hours after our pets eat. This sticky, transparent layer is not just saliva — it harbours bacteria that multiply and overgrow.
Worse, plaque shields the harmful bacteria, making them up to 1,000 times more resistant to antibacterial agents.
As plaque builds up, it hardens into tartar (calculus) - a thick, yellowish layer often mistaken for plaque. Unlike plaque, tartar cannot be brushed away and requires professional cleaning by a vet. Both plaque and tartar create rough surfaces where harmful bacteria easily attach and spread.
The first sign of trouble is bad breath, followed by Gingivitis, an early-stage gum disease that causes painful inflammation. Left untreated, this worsens into Periodontitis, where infection spreads deep under the gums, leading to tooth loss and severe discomfort.
Even more concerning, harmful bacteria can enter the bloodstream, affecting vital organs like the heart, liver, and kidneys. Without intervention, what starts as plaque may turn into a serious health issue for our pets.
Breaking down dental plaque
Kalzyme's proprietary enzyme blend mimics toothbrushing by breaking the bonds in plaque through hydrolysis instead of mechanical force and abrasion. This disperses harmful bacteria attached to the plaque.
Reducing bacteria adhesion & healing the gums
With daily use, the enzymes continuously break down plaque, while the other ingredients support gum healing. This forms a protective layer to prevent buildup of plaque, tartar and dental disease-causing bacteria.
Balancing the oral microbiome
Kalzyme is engineered to preserve the beneficial bacteria and allows it to repopulate. This helps to rebalance the oral microbiome for long-term dental health.
Kalzyme Dental Spray combines an advanced enzyme technology with clinically-backed results to create a gentle and effective solution for pet owners around the world.
Reach out to us for more information on placebo-controlled and case studies.
Simplify Dental Care For Your Cats
"I can’t say enough good things about Kalzyme's dental spray!
As a cat owner, I always worried about my cats' dental health, but relying solely on brushing teeth was a constant battle, especially when it took so much time to brush all the cats.
The spray is such a breeze to use and just take seconds to give me a sense of relief that I haven't skipped my dental duties.
A few cats had thick plaque and using the spray combined with brushing teeth made a huge difference in reducing the plaque!"
@twinklethekween
Gentle and Effective Formula For Your Dogs
"Sumo loving to brush his teeth now! When we used to use the toothbrush he'd struggle and made it very challenging to brush and keep his teeth clean.
Ever since we started using Kalzyme in March 2024, his back teeth transformed from yellow to white! In general his teeth and breath has improved significantly! We continue to use Kalzyme because not only it's effective, as you can see Sumo LOVES it!"
@speightandskittle
Our pets’ skin is home to a diverse community of microorganisms that make up the skin microbiome. These microbes coexist harmoniously with their immune system.
When balanced, these microbes support skin health by naturally outcompeting harmful bacteria and fungi.
However, an imbalance, often caused by an overgrowth of harmful microbes, can lead to bacterial or fungal infections, compromising our pets’ skin health.
Bacterial or fungal infections like yeast or ringworm can arise for various reasons. Identifying the cause is key to effective management and treatment.
- Food & environmental allergies often cause an immune response, triggering inflammation and itching. Repeated scratching breaks the skin barrier, leading to secondary infections.
- Underlying health issues can weaken the immune system, making our pets more susceptible to harmful bacterial & fungal overgrowth.
- Humid climates such as in Southeast Asia, promote bacterial & fungal overgrowth, increasing infection risk.
Bacteria & fungi on the skin produce biofilm, a sticky transparent layer comprising starch and protein.
Biofilms shield bacteria & fungi, making them up to 1,000 times more resistant to antimicrobial agents. As the harmful microbes overgrow, the immune system triggers an inflammatory response, leading to red, itchy patches.
Nibbling and scratching can create open wounds, allowing bacteria & fungi to enter the bloodstream, raising the risk of complications.
Breaking down the biofilm
Kalzyme’s proprietary enzyme blend break down the biofilm formed by bacteria and fungi through hydrolysis. This disperses the harmful bacteria and fungi protected within it.
Reducing bacteria adhesion & healing the skin
As the enzymes break down the biofilm, the formula also aids skin repair. This combats the active infection and creates a protective barrier to prevent harmful bacteria and fungi overgrowth.
Balancing the oral microbiome
Unlike antibacterial or antifungal agents, Kalzyme is engineered to preserve the beneficial microorganisms, allowing them to thrive. This helps to rebalance the skin microbiome for long-term skin health.
Kalzyme Dermal Spray and Gel combines an advanced enzyme technology with clinically-backed results to create a gentle and effective solution for pet owners around the world.
Reach out to us for more information on placebo-controlled and case studies.
Gentle and Effective Enzyme-Based Formula
"NEED TO SHARE! Legit. Took awhile for the hot spot area to grow back her fur, but it is not steroids!"
@sosisinyishun
Great For Bacterial and Fungal Infections
"Hooman applies Kalzyme on my paws every night before I sleep and after a month, my paws are much better yay!"
@pepe.the.pomsky
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Take control of your pet's dental and skin health today
